Recently, it has been shown that the Mitochondrial aldehyde dehydrogenase is responsible for the bioactivation of nitroglycerin prior to the release of NO, which is a strong vasodilator.

近来，有研究表明线醛脱酶是内催化硝酸甘油生物转化的主要途径，线醛脱酶同有脱酶和酯酶的催化活性，其酯酶活性可以通过将硝酸甘油脱硝形成一氧化氮，进而血管扩张。