The Prime Minister's policy alienated many of her followers.

首相政策使很多拥护她疏远了她。

The argument estranged him from his brother.

争吵使他同他兄弟之间关疏远了。

Man's family relations became a part of the legal conception of his life, and the alienation of a wife's affections was held remediable.

家庭关生活中法律概念，由于夫妻关产生疏远可以挽回。